Mclazide-M Tablet

Safety advice

AlcoholUNSAFE

It is unsafe to consume alcohol with Mclazide-M Tablet.

PregnancyCONSULT YOUR DOCTOR

Mclazide-M Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

BreastfeedingCONSULT YOUR DOCTOR

Mclazide-M Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

DrivingCAUTION

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

KidneyCAUTION

Mclazide-M Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mclazide-M Tablet may be needed. Please consult your doctor.Use of Mclazide-M Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

LiverCAUTION

Mclazide-M Tablet should be used with caution in patients with liver disease. Dose adjustment of Mclazide-M Tablet may be needed. Please consult your doctor.Mclazide-M Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

About this medicine

Uses

How to use

How it works

Side effects

Expert advice

Frequently asked questions

What is Mclazide-M Tablet?

Mclazide-M Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

What are the possible side effects of Mclazide-M Tablet?

The use of Mclazide-M Tablet is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Mclazide-M Tablet cause hypoglycemia?

Yes, the use of Mclazide-M Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Can the use of Mclazide-M Tablet cause lactic acidosis?

Yes, the use of Mclazide-M Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Mclazide-M Tablet and immediately consult your doctor.

Can the use of Mclazide-M Tablet lead to Vitamin B12 deficiency?

Yes, the use of Mclazide-M Tablet can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Are there any specific conditions in which Mclazide-M Tablet should not to be taken?

The use of Mclazide-M Tablet should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Mclazide-M Tablet?

No, it is not safe to take alcohol along with Mclazide-M Tablet. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

What is Mclazide-M Tablet?

Mclazide-M Tablet is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

What are the possible side effects of Mclazide-M Tablet?

The use of Mclazide-M Tablet is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Can the use of Mclazide-M Tablet cause hypoglycemia?

Yes, the use of Mclazide-M Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Can the use of Mclazide-M Tablet cause lactic acidosis?

Yes, the use of Mclazide-M Tablet can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Mclazide-M Tablet and immediately consult your doctor.

Can the use of Mclazide-M Tablet lead to Vitamin B12 deficiency?

Yes, the use of Mclazide-M Tablet can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Are there any specific conditions in which Mclazide-M Tablet should not to be taken?

The use of Mclazide-M Tablet should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Mclazide-M Tablet?

No, it is not safe to take alcohol along with Mclazide-M Tablet. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.